The Spectral Dependence for UVA-Induced Cumulative Damage in Human Skin
نویسندگان
چکیده
منابع مشابه
The specificity of UVA-induced DNA damage in human melanocytes.
Exposure to solar UV radiation is the origin of most skin cancers, including deadly melanomas. Melanomas are quite different from keratinocyte-derived tumours and exhibit a different mutation spectrum in the activated oncogenes, possibly arising from a different class of DNA damage. In addition, some data suggest a role for UVA radiation in melanomagenesis. To get further insight into the molec...
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BACKGROUND The use of psoralen-UVA (PUVA) in patients of skin phototype I to II is limited by side effects of acute phototoxicity and possible long-term carcinogenesis. OBJECTIVE We sought to assess oral Polypodium leucotomos (PL) extract in decreasing PUVA-induced phototoxicity of human skin on a clinical and histologic level. METHODS A total of 10 healthy patients with skin phototypes II ...
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In the present work, under some di¤erentiability conditions on the potential functions , we rst reduce the inverse scattering problem (ISP) for the polynomial pencil of the Scroedinger equation to the corresponding ISP for the generalized matrix Scrödinger equation . Then ISP will be solved in analogy of the Marchenko method. We aim to establish an e¤ective algorithm for uniquely reconstructin...
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UVA light (320-400 nm) represents approximately 95% of the total solar UV radiation that reaches the Earth's surface. UVA light induces oxidative stress and the formation of DNA photoproducts in skin cells. These photoproducts such as pyrimidine dimers (cyclobutane pyrimidine dimers, CPDs, and pyrimidine (6-4) pyrimidone photoproducts, 6-4PPs) are removed by nucleotide excision repair (NER). In...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1997
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12285613